Smart Anticancer Nanofibers: Hyperthermia Nanofiber Platform Synergized by Sustained Release of Paclitaxel to Improve Antitumor Efficiency (Adv. Healthcare Mater. 13/2019). Issue 13 (11th July 2019)

• Record Type: Journal Article
• Authors: Niiyama, Eri; Uto, Koichiro; Lee, Chun Man; Sakura, Kazuma; Ebara, Mitsuhiro
• Is Part Of: Advanced healthcare materials. Volume 8:Issue 13(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-07-11
• Subjects: combination cancer therapy -- hyperthermia -- nanofibers -- paclitaxel -- synergistic effects; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201970050
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : In article number 1900102, Mitsuhiro Ebara and co‐workers demonstrate the antitumor effect of a nanofiber mesh that can deliver heat and antitumor drugs in a controlled manner. The mesh generates heat when the loaded magnetic particles are activated in a magnetic field. The thermochemotherapy combination displays enhanced antitumor activity and the systemic toxic effects can be eliminated due to local release of the chemotherapeutic agents.