Black Swans of CRISPR: Stochasticity and Complexity of Genetic Regulation. (15th May 2019)

• Record Type: Journal Article
• Authors: Cheong, Kang Hao; Koh, Jin Ming; Jones, Michael C.
• Is Part Of: BioEssays. Volume 41:Number 7(2019:Jul.)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-05-15
• Subjects: biotechnology -- CRISPR -- gene regulatory networks -- genetic editing -- noise -- nonlinear dynamics -- stochasticity; Molecular biology -- Periodicals; Cytology -- Periodicals; Developmental biology -- Periodicals; 572.8
• DOI: 10.1002/bies.201900032
• Languages: English
• ISSNs: 0265-9247

Abstract

Abstract : Recent waves of controversies surrounding genetic engineering have spilled into popular science in Twitter battles between reputable scientists and their followers. Here, a cautionary perspective on the possible blind spots and risks of CRISPR and related biotechnologies is presented, focusing in particular on the stochastic nature of cellular control processes.