Visualization of corneal vascularization in peripheral hypertrophic subepithelial corneal opacification with OCT angiography. Issue 8 (19th April 2018)

• Record Type: Journal Article
• Authors: Riedl, Jana C.; Wasielica‐Poslednik, Joanna; Weyer‐Elberich, Veronika; Vossmerbaeumer, Urs; Pfeiffer, Norbert; Lisch, Walter; Gericke, Adrian
• Is Part Of: Acta ophthalmologica. Volume 96:Issue 8(2018)
• Page Start: e974
• Page End: e978
• Publication Date: 2018-04-19
• Subjects: angio‐OCT -- corneal epithelial thickness -- corneal neovascularization -- corneal thickness -- Fourier‐domain optical coherence tomography -- peripheral hypertrophic subepithelial corneal opacification -- Salzmann's degeneration; Ophthalmology -- Periodicals; 617.7005
• DOI: 10.1111/aos.13800
• Languages: English
• ISSNs: 1755-375X

Abstract

Abstract: Purpose: The major goal of this study was to test the hypothesis that in patients with peripheral hypertrophic subepithelial corneal opacification (PHSCO), visualization of corneal vessels is better with optical coherence tomography angiography (OCTA) than with conventional slit lamp microphotography. Methods: Patients with PHSCO were included in this prospective study. The corneal findings were photographed using a slit lamp camera (Haag Streit BM 900 ® ) and visualized with anterior‐segment OCT (Optovue XR Avanti, Fremont, California, USA). Additionally, OCTA with the Angiovue Imaging™ System was performed in the area of PHSCO. Results: Thirty‐four eyes of 19 patients (26% male and 74% female) with PHSCO were included in this study. In 21 eyes, vascularization in the area of PHSCO was visualized with the Angiovue‐OCT, whereas only 10 eyes presented vessels in slit lamp photographs. Conclusion: Optical coherence tomography angiography allows better visualization of corneal neovascularization than slit lamp photography in patients with PHSCO. Corneal opacifications were found predominantly nasally, which was reflected by a local enlargement of corneal thickness.