Studies on the Laccase‐Catalyzed Oxidation of 4‐Hydroxy‐Chalcones. Issue 11 (12th April 2019)

• Record Type: Journal Article
• Authors: Grosso, Simone; Radaelli, Fabio; Fronza, Giovanni; Passarella, Daniele; Monti, Daniela; Riva, Sergio
• Is Part Of: Advanced synthesis & catalysis. Volume 361:Issue 11(2019)
• Page Start: 2696
• Page End: 2705
• Publication Date: 2019-04-12
• Subjects: Laccase -- Chalcones -- 2, 3-Dihydrobenzofuran -- Oxidation -- Biocatalysis; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201900190
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: The laccase‐catalyzed oxidation of a series of substituted 4‐hydroxy‐chalcones has been investigated. The main isolated dimeric products were, as expected, racemic mixtures of trans ‐2, 3‐dihydrobenzofuran derivatives, always co‐eluted with an additional isomeric dimer with an open structure. The two enantiomers, as well as the co‐eluted dimeric isomer could be isolated by semi‐preparative HPLC with a chiral column and were fully characterized. Abstract :