Efficient Aerobic Oxidation of trans‐2‐Hexen‐1‐ol using the Aryl Alcohol Oxidase from Pleurotus eryngii. Issue 11 (7th February 2019)

• Record Type: Journal Article
• Authors: de Almeida, T. P.; van Schie, M. M. C. H.; Ma, A.; Tieves, F.; Younes, S. H. H.; Fernández‐Fueyo, E.; Arends, I. W. C. E.; Riul, A.; Hollmann, F.
• Is Part Of: Advanced synthesis & catalysis. Volume 361:Issue 11(2019)
• Page Start: 2668
• Page End: 2672
• Publication Date: 2019-02-07
• Subjects: biocatalysis -- oxidase -- two liquid phase system -- oxidation reactions; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201801312
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: The selective oxidation of trans ‐2‐hexen‐1‐ol to the corresponding aldehyde using a recombinant aryl alcohol oxidase from Pleurotus eryngii ( Pe AAOx) is reported. Especially using the two liquid phase system to overcome solubility and product inhibition issues enabled to achieve more than 2.200.000 catalytic turnovers for the production enzyme as well as molar product concentrations, pointing towards an economic feasible reaction. Abstract :