Systematic overview of neuroanatomical differences in ADHD: Definitive evidence. Issue 1 (2nd January 2018)

• Record Type: Journal Article
• Authors: Vieira de Melo, Bruno Bastos; Trigueiro, Maria João; Rodrigues, Pedro Pereira
• Is Part Of: Developmental neuropsychology. Volume 43:Issue 1(2018)
• Page Start: 52
• Page End: 68
• Publication Date: 2018-01-02
• Subjects: Neuropsychology -- Periodicals; 612.8
• DOI: 10.1080/87565641.2017.1414821
• Languages: English
• ISSNs: 8756-5641

Abstract

ABSTRACT: Objectives : This article seeks to identify neuroanatomical differences in ADHD through an overview of systematic reviews that report encephalic differences compared to a control group in volume, area, activation likelihood or chemical composition. Methods : We conducted a systematic search using Cochrane guidelines and PRISMA criteria in PubMed, Scopus, Web of Science, Cochrane Database of Systematic Reviews and Database of Abstracts of Reviews of Effects. Results : Results revealed broad encephalic involvement that includes a functional frontal and cingulate hypoactivation and structural differences in corpus callosum, cerebellum and basal nuclei. Conclusions : ADHD symptoms might be due to a multi-network unbalanced functioning hypothesis.