Individual and binary mixture effects of bisphenol A and lignin-derived bisphenol in Daphnia magna under chronic exposure. (January 2018)

• Record Type: Journal Article
• Authors: Li, Dan; Chen, Hongxing; Bi, Ran; Xie, Haibo; Zhou, Yu; Luo, Yongju; Xie, Lingtian
• Is Part Of: Chemosphere. Volume 191(2018)
• Page Start: 779
• Page End: 786
• Publication Date: 2018-01
• Subjects: Daphnia magna -- Bisphenol A -- Lignin-derived bisphenol -- Binary mixture -- Biochemical markers; Pollution -- Periodicals; Pollution -- Physiological effect -- Periodicals; Environmental sciences -- Periodicals; Atmospheric chemistry -- Periodicals; 551.511
• DOI: 10.1016/j.chemosphere.2017.10.022
• Languages: English
• ISSNs: 0045-6535

Abstract

Abstract: In recent years, many new chemicals have been synthesized from biomass with an aim for sustainable development by replacing the existing toxic chemicals with those having similar properties and applications. However, the effects of these new chemicals on aquatic organisms remain relatively unknown. In this study, the effects of bisphenol A (BPA) and lignin-derived bisphenol (LD-BP, a BPA analogue) on Daphnia magna were evaluated. The animals were exposed to BPA, LD-BP, and their binary mixture at concentrations (2–2000 μg L −1 ) for 21 days. The expression of various biochemical markers and the effects on growth, molting, and reproduction parameters were examined. The results showed that the weight of daphnids significantly increased after exposure to BPA, LD-BP, and the binary mixture relative to that of the control animals. The activity of superoxide dismutase was significantly inhibited by LD-BP and the binary mixture. At the highest exposure concentration of the binary mixture, the activities of acetylcholinesterase and α-glucosidase, fecundity, and the number of neonates per brood were significantly altered. Our results showed that the effects of BPA and LD-BP on D. magna were generally comparable, except for the effect on the weight at their environmentally relevant concentrations (e.g., <20 μg L −1 ). The effects on the reproduction of D. magna could be mainly due to the shift in energy redistribution under BPA and LD-BP exposures. Our results implied that exposures to both BPA and LD-BP could potentially cause deleterious effects at the population level in D. magna . Highlights: Exposure to the mixture of BPA and LD-BP increased the weight of Daphnia magna. SOD activity was inhibited by LD-BP and the binary mixture. BPA and LD-BP (2000 μg/L) alter the activity of AChE and α-Glu, and reproduction parameters. The mixture of bisphenols poses threat to Daphnia magna population.