Persistent eosinophilia among 21 historic cases of Strongyloides stercoralis infection: a case for routine follow-up and repeat treatment. (5th November 2019)

• Record Type: Journal Article
• Authors: Arkell, Paul; Cosgrove, Catherine; Riley, Peter
• Is Part Of: Transactions of the Royal Society of Tropical Medicine and Hygiene. Volume 114:Number 2(2020)
• Page Start: 137
• Page End: 139
• Publication Date: 2019-11-05
• Subjects: chronic infection -- eosinophilia -- ivermectin -- relapse -- Strongyloides stercoralis -- treatment; Tropical medicine -- Periodicals; 616.9883
• DOI: 10.1093/trstmh/trz085
• Languages: English
• ISSNs: 0035-9203

Abstract

Abstract: Background: Strongyloidasis affects more than 100 million people worldwide and causes persisting infection. Methods: We retrospectively reviewed 21 cases of parasitologically confirmed Strongyloides stercoralis infection at our centre. Results: We found four individuals who had eosinophilia (>0.5x10 9 /litre) more than 6 mo after treatment. Conclusions: This may represent ongoing or relapsed infection. Our data support the need for continued follow-up of treated individuals, particularly those with abnormal host defences who are at risk of severe forms of the disease.