Advances and Impact of Antioxidant Hydrogel in Chronic Wound Healing. Issue 5 (24th January 2020)

• Record Type: Journal Article
• Authors: Xu, Zejun; Han, Shuyan; Gu, Zhipeng; Wu, Jun
• Is Part Of: Advanced healthcare materials. Volume 9:Issue 5(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-01-24
• Subjects: antioxidants -- chronic wound healing -- hydrogels; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201901502
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract: The accelerating and thorough treatment of chronic wounds still represents a major unmet medical need owing to the complex symptoms resulting from metabolic disorder of the wound microenvironment. Although numerous strategies and bioactive hydrogels are developed, an effective and widely used method of chronic wound treatment remains a bottleneck. With the aim to accelerate chronic wound healing, many hydrogel dressings with antioxidant functions have emerged and are proven to accelerate wound healing, especially for chronic wound repair. The new strategy in chronic wound treatment brought by antioxidant hydrogels is of great significance to human health. Here, the application of antioxidant hydrogels in the repair of chronic wounds is discussed systematically, aiming to provide an important theoretical reference for the further breakthrough of chronic wound healing. Abstract : Antioxidant hydrogel dressings are proved to be effective in accelerating chronic wound healing. Meanwhile, antioxidant hydrogels for chronic wound healing include three main types: 1) antioxidant matrixes constructing hydrogels; 2) hydrogels containing antioxidation drugs; 3) hydrogels containing multifunctional antioxidants.