Neuron Culture Systems: Astrocyte‐Encapsulated Hydrogel Microfibers Enhance Neuronal Circuit Generation (Adv. Healthcare Mater. 5/2020). Issue 5 (4th March 2020)

• Record Type: Journal Article
• Authors: Kim, Beom Jin; Choi, Ji Yu; Choi, Hyunwoo; Han, Sol; Seo, Jeongyeon; Kim, Jungnam; Joo, Sunghoon; Kim, Hyo Min; Oh, Chungik; Hong, Seungbum; Kim, Pilnam; Choi, Insung S.
• Is Part Of: Advanced healthcare materials. Volume 9:Issue 5(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-03-04
• Subjects: astrocytes -- cell encapsulation -- neuron culture systems -- primary hippocampal neurons; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.202070013
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : In article number 1901072 by Insung S. Choi and co‐workers, a 3D neuron‐culture system is fabricated by encapsulating astrocytes (green in the picture) in alginate microfibers and culturing hippocampal neurons (orange) on the aligned microfibers. The astrocyte‐laden microfibers enhance neurite outgrowth and synaptic formation as well as controlling the outgrowth directionality, suggesting a cytotherapeutic platform for neural injuries. The image was designed by co‐authors Sol Han and Hyunwoo Choi.