Cervical lymph node metastasis of ovarian dysgerminoma: A case report with fine needle aspiration cytology. Issue 4 (30th December 2019)

• Record Type: Journal Article
• Authors: Maekawa, Kazunari; Tokumitsu, Takako; Minematsu, Eiko; Noguchi, Hiroshi; Nakamura, Eriko; Asada, Yujiro; Nakayama, Tetsuo; Sameshima, Hiroshi; Sato, Yuichiro
• Is Part Of: Diagnostic cytopathology. Volume 48:Issue 4(2020)
• Page Start: 356
• Page End: 359
• Publication Date: 2019-12-30
• Subjects: aspiration cytology -- dysgerminoma -- immunocytochemistry -- lymph node metastasis; Cytodiagnosis -- Periodicals; Pathology, Cellular -- Periodicals; Cytology -- Periodicals; 616.07582
• DOI: 10.1002/dc.24351
• Languages: English
• ISSNs: 8755-1039

Abstract

Abstract: Dysgerminoma is a rare germ cell tumor, accounting for 1% to 2% of all malignant ovarian tumors. Here, we report a case of dysgerminoma diagnosed by aspiration cytology of a cervical lymph node. A 20‐year‐old woman presented with an abdominal mass and left cervical swelling. CT revealed a large pelvic tumor, along with a nodular lesion on the left side of neck. Fine needle aspiration (FNA) cytology of a cervical lymph node showed large atypical cells and small lymphocytes. Immunocytochemical staining on cell block material revealed that these large tumor cells were positive for placental alkaline phosphatase, D2‐40, and c‐kit. Dysgerminoma was suggested by FNA cytology. Furthermore, bilateral oophorectomy was performed, and histology confirmed the diagnosis of ovarian dysgerminoma. FNA cytology of metastatic lymph nodes along with immunocytochemistry is a useful tool for diagnosis of dysgerminoma.