Dicer Functions in Aquatic Species. (9th June 2011)

• Record Type: Journal Article
• Authors: Kitagishi, Yasuko; Okumura, Naoko; Yoshida, Hitomi; Tateishi, Chika; Nishimura, Yuri; Matsuda, Satoru
• Other Names: Kishimura Hideki Academic Editor.
• Is Part Of: Journal of amino acids. Volume 2011(2011)
• Publication Date: 2011-06-09
• Subjects: Amino acids -- Periodicals; Amino Acids; Amino acids; Electronic journals; Periodical; Periodicals; 612.015756
• DOI: 10.4061/2011/782187
• Languages: English
• ISSNs: 2090-0404

Abstract

Abstract : Dicer is an RNase III enzyme with two catalytic subunits, which catalyzes the cleavage of double-stranded RNA to small interfering RNAs and micro-RNAs, which are mainly involved in invasive nucleic acid defense and endogenous genes regulation. Dicer is abundantly expressed in embryos, indicating the importance of the protein in early embryonic development. In addition, Dicer is thought to be involved in defense mechanism against foreign nucleic acids such as viruses. This paper will mainly focus on the recent progress of Dicer-related research and discuss potential RNA interference pathways in aquatic species.