Determining the Optimal Number of Stimuli per Cranial Site during Transcranial Magnetic Stimulation Mapping. (26th February 2017)

• Record Type: Journal Article
• Authors: Cavaleri, Rocco; Schabrun, Siobhan M.; Chipchase, Lucy S.
• Other Names: Bosco Gianfranco Academic Editor.
• Is Part Of: Neuroscience journal. Volume 2017(2017)
• Publication Date: 2017-02-26
• Subjects: Neurosciences -- Periodicals; 616.8005
• DOI: 10.1155/2017/6328569
• Languages: English
• ISSNs: 2314-4262

Abstract

Abstract : The delivery of five stimuli to each cranial site is recommended during transcranial magnetic stimulation (TMS) mapping. However, this time-consuming practice restricts the use of TMS mapping beyond the research environment. While reducing the number of stimuli administered to each cranial site may improve efficiency and decrease physiological demand, doing so may also compromise the procedure's validity. Therefore, the aim of this study was to determine the minimum number of stimuli per cranial site required to obtain valid outcomes during TMS mapping. Map volume and centre of gravity (CoG) recordings obtained using five stimuli per cranial site were retrospectively compared to those obtained using one, two, three, and four stimuli per cranial site. For CoG longitude, one stimulus per cranial site produced valid recordings (ICC = 0.91, 95% CI 0.82 to 0.95). However, this outcome is rarely explored in isolation. As two stimuli per cranial site were required to obtain valid CoG latitude (ICC = 0.99, 95% CI 0.99 to 0.99) and map volume (ICC = 0.99, 95% CI 0.99 to 0.99) recordings, it is recommended that a minimum of two stimuli be delivered to each cranial site during TMS mapping in order to obtain valid outcomes.