Investigation of catalytic activity of solid acidic Fecl3/bentonite catalyst on the synthesis of some (E)-1-(2, 4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-ones by solvent-free technique. (2020)

• Record Type: Journal Article
• Authors: Balaji, S.; Manikandan, V.; Rajarajan, M.; Usha, V.; Rajalakshmi, S.; Venkatachalam, P.; Muthuvel, I.; Thirunarayanan, G.
• Is Part Of: Materials today. Volume 22:Part 3(2020)
• Page Start: 931
• Page End: 936
• Publication Date: 2020
• Subjects: 2, 4-Dimethylthiazol enones -- FeCl3/Bentonite -- Greener synthesis -- Microwave irradiation -- Catalytic activity -- Effect of solvents; Materials science -- Congresses -- Periodicals; 620.1
• DOI: 10.1016/j.matpr.2019.11.113
• Languages: English
• ISSNs: 2214-7853

Abstract

Abstract: In this work, an attempt was made to synthesized more than 90% yields of ( E )-1-(2, 4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-one by cross-aldol condensation reaction of 5′acetyl 2, 4-dimethylthiazole with various substituted benzaldehydes in the presence solid acidic FeCl3 /Bentonite catalyst using microwave irradiation under solvent-free conditions. The synthesized ( E )-1-(2, 4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-one derivative was characterized by physical constants, UV, FT-IR, 1 H NMR and 13 C NMR spectral data. In this condensation, the effect of catalytic activity was investigated by the obtained yield of enones and reusability. This greener technique offered for high yield of 2, 4-dimethylthiazole enones.