Failures of once‐a‐week trimethoprim‐sulfamethoxazole prophylaxis in children undergoing allogeneic hematopoietic stem cell transplant. Issue 1 (27th December 2019)

• Record Type: Journal Article
• Authors: Castagnola, Elio; Mesini, Alessio; Saffioti, Carolina; Moscatelli, Andrea; Pierri, Filomena; Giardino, Stefano; Faraci, Maura
• Is Part Of: Transplant infectious disease. Volume 22:Issue 1(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-12-27
• Subjects: allogeneic hematopoietic stem cell transplant -- children -- Pneumocystis jirovecii pneumonia -- trimethoprim‐sulfamethoxazole prophylaxis; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.13231
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: Once‐a‐week cotrimoxazole is an effective prophylaxis for pneumocystosis during antineoplastic chemotherapy or autologous stem cell transplant. Following allogeneic stem cell transplant, this schedule is at risk of pneumocystosis or neurotoxoplasmosis, as demonstrated by these case reports. Therefore, a 3‐times‐a‐week schedule must be adopted in these patients.