Facile synthesis of a cyclodextrin-metal organic framework decorated with Ketjen Black and platinum nanoparticles and its application in the electrochemical detection of ofloxacin. Issue 5 (28th January 2020)

• Record Type: Journal Article
• Authors: Luan, Feng; Wang, Yunfei; Zhang, Shuang; Zhuang, Xuming; Tian, Chunyuan; Fu, Xiuli; Chen, Lingxin
• Is Part Of: Analyst. Volume 145:Issue 5(2020)
• Page Start: 1943
• Page End: 1949
• Publication Date: 2020-01-28
• Subjects: Chemistry, Analytic -- Periodicals; 543
• DOI: 10.1039/c9an02575h
• Languages: English
• ISSNs: 0003-2654

Abstract

Abstract : An electrochemical sensor for ofloxacin detection based on cyclodextrin-metal organic framework, Ketjen Black, and platinum nanoparticles. Abstract : A facile and novel method was developed to improve the conductivity of a cyclodextrin-metal organic frameworks (CD-MOFs) by modifying it with Ketjen Black (KB) and platinum nanoparticles (PtNPs). The structural morphology and composition of this PtNPs/KB/CD-MOFs nanocomposite was characterized by transmission electron microscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, elemental mapping, and Raman spectroscopy. The sensor was then evaluated for its ability to detect ofloxacin using cyclic voltammetry, and the results showed that the PtNPs/KB/CD-MOF had high sensitivity, satisfactory stability and good reproducibility. In addition, a great linear range was obtained with a concentration range of 0.08–100 μM and a low detection limit of 0.037 μM (S/N = 3). Therefore, the prepared electrochemical sensor could be successfully used to detect ofloxacin in serum.