No effects on appetite or body weight in weight-reduced individuals of foods containing components previously shown to reduce appetite - Results from the SATIN (Satiety Innovation) study. (March 2020)

• Record Type: Journal Article
• Authors: Andersen, Sarah Vold; Sandby, Karoline; Hjorth, Mads Fiil; Korndal, Sanne Kellebjerg; Ritz, Christian; Sjödin, Anders; Halford, Jason C.G.; Mead, Bethan R.; Christiansen, Paul; Harrold, Joanne A.; Camacho-Barcía, Lucia; García-Gavilán, Jesús Francisco; Salas-Salvadó, Jordi; Bulló, Mònica; Hansen, Thea Toft
• Is Part Of: Obesity medicine. Volume 17(2020)
• Publication Date: 2020-03
• Subjects: Food innovation -- Hunger -- Obesity -- Overweight -- Satiety; AE adverse events -- BMI body mass index -- CC complete case -- CI Confidence interval -- E% energy percentage -- GOS galactooligosaccharides -- iAUC incremental area under the curve -- IQR Interquartile range -- ITT intention-to-treat -- SD Standard deviation -- tAUC total area under the curve -- VAS visual analogue scales -- YGD Yerba mate, Guarana, and Damiana; Obesity -- Periodicals; Obesity; Obesity; Periodicals; Periodicals; 616.398005
• DOI: 10.1016/j.obmed.2020.100188
• Languages: English
• ISSNs: 2451-8476

Abstract

Abstract: Aims: The aim was to investigate the acute and sustained effects of foods previously shown to reduce appetite on appetite and weight loss maintenance. Methods: Following an 8-week weight loss phase achieving ≥ 8% weight loss and 7–10 days of weight-stabilization, participants underwent a double-blinded, randomized, parallel 12-week weight loss maintenance period with either one of three intervention products previously shown to reduce appetite or matching controls. Appetite probe days were completed at baseline, at the start of the weight loss maintenance (acute effects), and after the weight loss maintenance (sustained effects) along with body weight measurements. Results: In total, 197 participants entered the weight loss maintenance period and were included in intention-to-treat analyses. No differences in acute or sustained effects on appetite were observed between the intervention and control groups for any of the three products (24-h energy intake: all P ≥ 0.63; overall appetite suppression score assessed by visual analogue scales: all P ≥ 0.14). Also, no difference in body weight was observed (all P ≥ 0.62). Conclusions: Exposure to specific foods previously shown to reduce appetite was not found to reduce appetite acute or sustained or to improve weight loss maintenance as compared to control products in weight-reduced individuals.