Alternating patterns of seasonal influenza activity in the WHO European Region following the 2009 pandemic, 2010‐2018. Issue 2 (16th January 2020)

• Record Type: Journal Article
• Authors: Mook, Piers; Meerhoff, Tamara; Olsen, Sonja J.; Snacken, René; Adlhoch, Cornelia; Pereyaslov, Dmitriy; Broberg, Eeva K.; Melidou, Angeliki; Brown, Caroline; Penttinen, Pasi
• Other Names: Simaku Artan investigator.; Hasibra Iris investigator.; Torosyan Liana investigator.; Sargsyan Shushan investigator.; Redlberger‐Fritz Monika investigator.; Aberle Judith H investigator.; Salimov Oleg investigator.; Abdullayeva Nazakat investigator.; Shimanovich Veronika investigator.; Gribkova Natalia investigator.; Bossuyt Nathalie investigator.; Thomas Isabelle investigator.; Kurchatova Anna investigator.; Korsun Neli investigator.; Petrović Goranka investigator.; Draženović Vladimir investigator.; Koliou Maria investigator.; Pieridou Despo investigator.; Havlickova Martina investigator.; Kyncl Jan investigator.; Krause Tyra Grove investigator.; Trebbien Ramona investigator.; Sadikova Olga investigator.; Kuznetsova Natalja investigator.; Enouf Vincent investigator.; Bernard‐Stoecklin Sibylle investigator.; Ikonen Niina investigator.; Lyytikäinen Outi investigator.; Machablishvili Ann investigator.; Zakhashvili Khatuna investigator.; Buda Silke investigator.; Dürrwald Ralf investigator.; Kalkouni Ourania investigator.; Gioula Georgia investigator.; Molnár Zsuzsanna investigator.; Rózsa Mónika investigator.; Dunford Linda investigator.; O Donnell Joan investigator.; Sigmundsdottir Gudrun investigator.; Baldvinsdottir Gudrun Erna investigator.; Kaufman Zalman investigator.; Mandelboim Michal investigator.; Rizzo Caterina investigator.; Castrucci Maria Rita investigator.; Meirim Sultanova investigator.; Sagimbay Altynay investigator.; Dinagul Otorbaeva investigator.; Azat Bodoshev investigator.; Nikiforova Raina investigator.; Zamjatina Natalija investigator.; Skrickienė Asta investigator.; Griškevičius Algirdas investigator.; Fournier Guillaume investigator.; Mossong Joel investigator.; Melillo Jackie M investigator.; Zahra Graziella investigator.; Rakočević Božidarka investigator.; Vratnica Zoran investigator.; Donker Gé investigator.; Meijer Adam investigator.; Bosevska Golubinka investigator.; Mikikj Vladimir investigator.; Paulsen Trine Hessevik investigator.; Hunges Olav investigator.; Brydak Lidia B investigator.; Luniewska Katarzyna investigator.; Guiomar Raquel investigator.; Rodrigues Ana Paula investigator.; Gheorghita Stefan investigator.; Spinu Constantin investigator.; Popescu Rodica investigator.; Ivanciuc Alina investigator.; Sominina Anna A investigator.; Burtseva Elena investigator.; Dimitrijevic Dragana investigator.; Filipovic‐Vignjevic Svetlana investigator.; Kalaveshi Arijana investigator.; Sočan Maja investigator.; Prosenc Katarina investigator.; Bakoss Ivan investigator.; Staroňová Edita investigator.; Larrauri Amparo investigator.; Pozo Francisco investigator.; Carnahan AnnaSara investigator.; Brytting Mia investigator.; Perisa Damir investigator.; Gonçalves Ana Rita investigator.; Safarova Tamanno investigator.; Zakirova Niginamo investigator.; Avci Emine investigator.; Altas Ayse Basak investigator.; Artemchuk Oksana investigator.; Demchishyna Iryna investigator.; Pebody Richard investigator.; Ellis Joanna investigator.; McCaughey Conall investigator.; O'Doherty Mark investigator.; Mcmenamin Jim investigator.; Reynolds Arlene investigator.; Cottrell Simon investigator.; Moore Catherine investigator.; Djemileva Sultana investigator.; Rakhimov Ravshan investigator.; McCauley John investigator.; Daniels Rod investigator.;
• Is Part Of: Influenza and other respiratory viruses. Volume 14:Issue 2(2020)
• Page Start: 150
• Page End: 161
• Publication Date: 2020-01-16
• Subjects: Central Asia -- Europe -- influenza -- surveillance; Influenza -- Periodicals; Respiratory infections -- Periodicals; Virus diseases -- Periodicals; Influenza, Human -- Periodicals; Respiratory Tract Diseases -- Periodicals; Virus Diseases -- Periodicals; Grippe -- Périodiques; Appareil respiratoire -- Infections -- Périodiques; Maladies à virus -- Périodiques; 616.203
• DOI: 10.1111/irv.12703
• Languages: English
• ISSNs: 1750-2640

Abstract

Abstract: Background: Influenza virus infections are common and lead to substantial morbidity and mortality worldwide. We characterized the first eight influenza epidemics since the 2009 influenza pandemic by describing the distribution of viruses and epidemics temporally and geographically across the WHO European Region. Methods: We retrospectively analyzed laboratory‐confirmed influenza detections in ambulatory patients from sentinel sites. Data were aggregated by reporting entity and season (weeks 40‐20) for 2010‐2011 to 2017‐2018. We explored geographical spread using correlation coefficients. Results: There was variation in the regional influenza epidemics during the study period. Influenza A virus subtypes alternated in dominance, except for 2013‐2014 during which both cocirculated, and only one season (2017‐2018) was B virus dominant. The median start week for epidemics in the Region was week 50, the time to the peak ranged between four and 13 weeks, and the duration of the epidemic ranged between 19 and 25 weeks. There was evidence of a west‐to‐east spread across the Region during epidemics in 2010‐2011 ( r = .365; P = .019), 2012‐2013 ( r = .484; P = .001), 2014‐2015 ( r = .423; P = .006), and 2017‐2018 ( r = .566; P < .001) seasons. Variation in virus distribution and timing existed within reporting entities across seasons and across reporting entities for a given season. Conclusions: Aggregated influenza detection data from sentinel surveillance sites by season between 2010 and 2018 have been presented for the European Region for the first time. Substantial diversity exists between influenza epidemics. These data can inform prevention and control efforts at national, sub‐national, and international levels. Aggregated, regional surveillance data from early affected reporting entities may provide an early warning function and be helpful for early season forecasting efforts.