Switching enzyme activity by a temperature responsive inhibitor modified polymer. Issue 16 (30th January 2020)
- Record Type:
- Journal Article
- Title:
- Switching enzyme activity by a temperature responsive inhibitor modified polymer. Issue 16 (30th January 2020)
- Main Title:
- Switching enzyme activity by a temperature responsive inhibitor modified polymer
- Authors:
- Rottke, Falko O.
Heyne, Marie-Victoria
Reinicke, Stefan - Abstract:
- Abstract : A thermoresponsive NIPAAm-based polymer is combined with the selective acetylcholinesterase inhibitor tacrine in order to create a strict in sense on/off switch for enzyme activity. Abstract : A thermoresponsive NIPAAm-based polymer is combined with the selective acetylcholinesterase inhibitor tacrine in order to create a strict in sense on/off switch for enzymatic activity. This polymer–inhibitor conjugate inhibits AChE at room temperature and enables reactivation of AChE by heating above the cloud point of the conjugate.
- Is Part Of:
- Chemical communications. Volume 56:Issue 16(2020)
- Journal:
- Chemical communications
- Issue:
- Volume 56:Issue 16(2020)
- Issue Display:
- Volume 56, Issue 16 (2020)
- Year:
- 2020
- Volume:
- 56
- Issue:
- 16
- Issue Sort Value:
- 2020-0056-0016-0000
- Page Start:
- 2459
- Page End:
- 2462
- Publication Date:
- 2020-01-30
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c9cc09385k ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 12911.xml