Dendritic cell development: A personal historical perspective. (March 2020)

• Record Type: Journal Article
• Authors: Shortman, Ken
• Is Part Of: Molecular immunology. Volume 119(2020:Mar.)
• Page Start: 64
• Page End: 68
• Publication Date: 2020-03
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2019.12.016
• Languages: English
• ISSNs: 0161-5890

Abstract

Abstract: Dendritic cells(DCs) were once considered as a single cell type closely related developmentally to macrophages. Now we recognise several subtypes of DCs and have outlined several different pathways that potentially lead to their development. This article outlines some of the research findings that led to these changes in perspective, from the point of view of one of the participants.