A case of ALS with posterior cortical atrophy. Issue 7 (2nd October 2019)

• Record Type: Journal Article
• Authors: Nijboer, Tanja C. W.; Nitert, Bram; Westeneng, Henk-Jan; Van Den Berg, Leonard H.; van Es, Michael A.
• Is Part Of: Amyotrophic lateral sclerosis and frontotemporal degeneration. Volume 20:Issue 7/8(2019)
• Page Start: 506
• Page End: 510
• Publication Date: 2019-10-02
• Subjects: Amyotrophic lateral sclerosis -- posterior cortical atrophy -- MND-FTD continuum; 616.839
• DOI: 10.1080/21678421.2019.1632348
• Languages: English
• ISSNs: 2167-8421

Abstract

Abstract: Here, we provide a case-report of an amyotrophic lateral sclerosis (ALS) patient with cognitive deficits best defined as posterior cortical atrophy (PCA). This is an unusual finding as ALS forms a spectrum with frontotemporal dementia (FTD), whereas PCA is predominantly associated with Alzheimer's disease pathology. We hypothesize on whether ALS with PCA might be an under recognized phenotype considering multiple imaging studies in ALS have also reported (asymptomatic) parietal atrophy.