New dibenzodioxocinone and pyran-3, 5-dione derivatives from the deep-sea-derived fungus Penicillium canescens SCSIO z053. Issue 4 (2nd April 2020)

• Record Type: Journal Article
• Authors: Dasanayaka, S. A. H. K.; Nong, Xu-Hua; Liang, Xiao; Liang, Jian-Qiu; Amin, Muhammad; Qi, Shu-Hua
• Is Part Of: Journal of Asian natural products research. Volume 22:Issue 4(2020)
• Page Start: 338
• Page End: 345
• Publication Date: 2020-04-02
• Subjects: Penicillium canescens -- dibenzodioxocinone -- pyrane-3, 5-diketone -- bioactivity; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2019.1575819
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: A new isopentylated dibenzodioxocinone, canescenin A (1 ), and a new isopentylated pyran-3, 5-dione derivative, canescenin B (2 ), were isolated from an extract of the deep-sea-derived fungus Penicillium canescens SCSIO z053. Their structures were elucidated by spectroscopic analysis. It was rare to obtain pyran-3, 5-dione derivatives from nature. Antibacterial, cytotoxic, and antiviral activities of 1 and 2 were also evaluated. Graphical Abstract: