Estimating the approximate analytical solution of HIV viral dynamic model by using homotopy analysis method. (February 2020)

• Record Type: Journal Article
• Authors: Naik, Parvaiz Ahmad; Zu, Jian; Ghoreishi, Mohammad
• Is Part Of: Chaos, solitons and fractals. Volume 131(2020)
• Publication Date: 2020-02
• Subjects: HIV viral dynamic model -- Homotopy analysis method (HAM) -- Stability analysis -- Lyapunov function -- Reproduction number ℜ0 -- Auxiliary parameter ℏ.; Chaotic behavior in systems -- Periodicals; Solitons -- Periodicals; Fractals -- Periodicals; Chaotic behavior in systems; Fractals; Solitons; Periodicals; 003.7
• DOI: 10.1016/j.chaos.2019.109500
• Languages: English
• ISSNs: 0960-0779

Abstract

Highlights: Approximate analytical solution of basic HIV viral dynamic model is obtained. HAM is applied to describe the HIV viral dynamic model. HAM presented in the article shows better efficiency and accuracy on the obtained results. The convergence theorem of HAM to the HIV viral dynamic model is proved. The solution is improved by applying the least squares method. Abstract: Viruses have different mechanisms in causing a disease in an organism, which largely depend on the viral species. The recent advancement, through coupling data analysis and mathematical modeling, has allowed the identification and characterization of the nature of the virus. In the present paper, the homotopy analysis method is applied to provide an approximate solution of the basic HIV viral dynamic model describing the viral dynamics in a susceptible population. The proposed method allows for the solution of the governing system of differential equations to be calculated in the form of an infinite series with components which can be easily calculated. The homotopy analysis method utilizes a simple method to adjust and control the convergence region of the infinite series solution by using an auxiliary parameter. By using the homotopy series solutions, firstly, several β − curves using an appropriate ratio are plotted to demonstrate the regions of convergence and the optimum value of ℏ, then the residual and absolute errors are obtained for different values of these regions. Secondly, the residual error functions are applied to show the accuracy of the applied homotopy analysis method. Also, the convergence theorem of homotopy analysis method for the HIV viral dynamic model is proved. Mathematica software is used for the calculations and numerical results. The results obtained show the effectiveness and strength of the homotopy analysis method.