Case report of eight pregnant women with syphilis. Issue 3 (March 2020)

• Record Type: Journal Article
• Authors: Nakasuji, Yukiko; Tanimura, Kenji; Sasagawa, Yuki; Imafuku, Hitomi; Morizane, Mayumi; Fujioka, Kazumichi; Ohji, Goh; Yamada, Hideto
• Is Part Of: Journal of infection and chemotherapy. Volume 26:Issue 3(2020:Mar.)
• Page Start: 298
• Page End: 300
• Publication Date: 2020-03
• Subjects: Amoxicillin -- Congenital syphilis -- Penicillin G -- Pregnancy -- Syphilis; Chemotherapy -- Periodicals; Infection -- Periodicals; Communicable diseases -- Chemotherapy -- Periodicals; 615.5805
• DOI: 10.1016/j.jiac.2019.10.016
• Languages: English
• ISSNs: 1341-321X

Abstract

Abstract: Congenital syphilis may lead to severe sequelae in affected infants. The prevalence of syphilis in women of childbearing age has increased worldwide. From 2015 to 2018, we encountered eight pregnant women with syphilis including six with late latent and two with early latent syphilis. Seven pregnant women with syphilis received antibiotic therapies of oral amoxicillin, intravenous penicillin G, or the both. The syphilotherapies in four cases were considered effective, because rapid plasma reagin titers decreased. None of the seven pregnant women who received syphilotherapies had congenital syphilis. The remaining one woman who did not undergo a maternity checkup or syphilotherapy delivered a stillbirth with congenital syphilis at 29 gestational weeks.