Secondary metabolites from the fungus Stereum gausapatum ATCC60954. (February 2020)

• Record Type: Journal Article
• Authors: Huang, Jun-Ran; Yang, Bang-Ju; Mo, Ming-He; Zhang, Ke-Qin; Li, Guo-Hong
• Is Part Of: Phytochemistry letters. Volume 35(2020)
• Page Start: 171
• Page End: 174
• Publication Date: 2020-02
• Subjects: Stereum gausapatum ATCC60954 -- Metabolites -- Sesquiterpene -- Nematicidal activity -- Spectroscopy analysis; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2019.12.004
• Languages: English
• ISSNs: 1874-3900

Abstract

Graphical abstract: Three new metabolites, strobilol N (1 ), strobilol O (2 ), strobilol P (3 ) were isolated from the fungus Stereum gausapatum ATCC60954. Highlights: This is the first report about the chemical constitutes of the fungus Stereum gausapatum . New metabolites strobilol N, strobilol O and strobilol P were obtained. Their structures were characterized by extensive 2D-NMR studies. Abstract: A phytochemical investigation of basidiomycete Stereum gausapatum ATCC60954 led to the isolation of five compounds. They are determined to be strobilol N (1 ), strobilol O (2 ), strobilol P (3 ), strobilol E (4 ) and stereumin D (5 ) based on the spectral data. Compounds 1 -3 are new metabolites. Compound 1 was active against nematode Caenorhabditiselegans with the mortality 75.8 % at 200 μg/ml in 36 h. This is the first report about the chemical constituents of fungus Stereum gausapatum .