Malignant Peripheral Nerve Sheath Tumor With Bilateral Adrenal Metastases: Role of 18F-FDG PET/CT in Response Assessment to Tyrosine Kinase Inhibitor and Liposomal Doxorubicin. (June 2019)

• Record Type: Journal Article
• Authors: Tripathy, Sarthak; Passah, Averilicia; Singhal, Abhinav; Prashanth, Arun; Kumar, Rakesh
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 6(2019)
• Publication Date: 2019-06
• Subjects: FDG -- MPNST -- adrenal -- metastasis -- PET/CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002542
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: MPNSTs (malignant peripheral nerve sheath tumors) are a highly malignant group of soft tissue sarcomas and carry a very poor prognosis. Metastasis to bilateral adrenal glands is very rare in such group of neoplasms. We discuss a case of 85-year-old man who was diagnosed with MPNST from prevertebral mass with metastases to bilateral adrenal glands and bone marrow from the beginning and role of serial 18 F-FDG PET/CT scans in response assessment first to sunitinib (tyrosine kinase inhibitor) and then to liposomal doxorubicin.