Comparison of the prognostic capability of two comorbidity indices in patients with chronic obstructive pulmonary disease, in real‐life clinical practice. (24th April 2019)

• Record Type: Journal Article
• Authors: Figueira‐Gonçalves, Juan Marco; Golpe, Rafael; García‐Bello, Miguel Ángel; García‐Talavera, Ignacio; Castro‐Añón, Olalla
• Is Part Of: Clinical respiratory journal. Volume 13:Number 6(2019)
• Page Start: 404
• Page End: 407
• Publication Date: 2019-04-24
• Subjects: Charlson comorbidity index -- chronic obstructive pulmonary disease -- comorbidity -- COTE index -- mortality -- prognosis; Respiratory organs -- Diseases -- Periodicals; Respiratory organs -- Periodicals; 616.24
• DOI: 10.1111/crj.13025
• Languages: English
• ISSNs: 1752-6981

Abstract

Abstract: Background: Comorbidities are a major cause of death in chronic obstructive pulmonary disease (COPD). The COPD‐comorbidity test (COTE) index was designed to measure comorbidity burden in this disease. The objective of this study was to compare the capability of COTE and the non‐COPD specific Charlson comorbidity index (CCI) to predict all‐cause mortality in real‐life conditions. Methods: Retrospective observational study, carried out in two different series of consecutive COPD patients including, respectively, 790 and 439 subjects. The COTE and non‐age‐adjusted CCI indices were calculated and the values of the C‐statistic for predicting all‐cause mortality were compared for both indices. Results: Median follow‐up was 54 months and there were 321 deaths within this period of time. The value of the C‐statistic for the CCI was significantly higher than for the COTE index in both groups. Conclusion: When used in real‐life clinical practice, the value of the CCI to predict all‐cause mortality in COPD seems higher than that of the COTE index.