Motor imagery based brain-computer interface control of continuous passive motion for wrist extension recovery in chronic stroke patients. (23rd January 2020)

• Record Type: Journal Article
• Authors: Lu, Rong-Rong; Zheng, Mou-Xiong; Li, Jie; Gao, Tian-Hao; Hua, Xu-Yun; Liu, Gang; Huang, Song-Hua; Xu, Jian-Guang; Wu, Yi
• Is Part Of: Neuroscience letters. Volume 718(2020)
• Publication Date: 2020-01-23
• Subjects: Stroke -- Rehabilitation -- Brain-computer interface -- Continuous passive motion -- motor imagery; Neurology -- Periodicals; Neurology -- Periodicals; Research -- Periodicals; Neurologie -- Périodiques; Neuroanatomie -- Périodiques; Neuropharmacologie -- Périodiques; Neurophysiologie -- Périodiques; Neurology; Periodicals; Electronic journals; 617.48
• DOI: 10.1016/j.neulet.2019.134727
• Languages: English
• ISSNs: 0304-3940

Abstract

Graphical abstract: Highlights: Twenty-one patients successfully recovered active wrist extension. Motor imagery based BCI control of wrist CPM training was applied. Typical spatial and spectrum patterns of ERD/ERS formed after training. Abstract: Motor recovery of wrist and fingers is still a great challenge for chronic stroke survivors. The present study aimed to verify the efficiency of motor imagery based brain-computer interface (BCI) control of continuous passive motion (CPM) in the recovery of wrist extension due to stroke. An observational study was conducted in 26 chronic stroke patients, aged 49.0 ± 15.4 years, with upper extremity motor impairment. All patients showed no wrist extension recovery. A 24-channel highresolution electroencephalogram (EEG) system was used to acquire cortical signal while they were imagining extension of the affected wrist. Then, 20 sessions of BCI-driven CPM training were carried out for 6 weeks. Primary outcome was the increase of active range of motion (ROM) of the affected wrist from the baseline to final evaluation. Improvement of modified Barthel Index, EEG classification and motor imagery pattern of wrist extension were recorded as secondary outcomes. Twenty-one patients finally passed the EEG screening and completed all the BCI-driven CPM trainings. From baseline to the final evaluation, the increase of active ROM of the affected wrists was (24.05 ± 14.46)˚. The increase of modified Barthel Index was 3.10 ± 4.02 points. But no statistical difference was detected between the baseline and final evaluations (P > 0.05). Both EEG classification and motor imagery pattern improved. The present study demonstrated beneficial outcomes of MI-based BCI control of CPM training in motor recovery of wrist extension using motor imagery signal of brain in chronic stroke patients.