Organocatalytic synthesis of 5‐hydroxyisoxazolidine catalyzed by camphor sulfonyl hydrazines through aza‐Michael addition/cyclization. Issue 3 (20th January 2020)
- Record Type:
- Journal Article
- Title:
- Organocatalytic synthesis of 5‐hydroxyisoxazolidine catalyzed by camphor sulfonyl hydrazines through aza‐Michael addition/cyclization. Issue 3 (20th January 2020)
- Main Title:
- Organocatalytic synthesis of 5‐hydroxyisoxazolidine catalyzed by camphor sulfonyl hydrazines through aza‐Michael addition/cyclization
- Authors:
- Xu, Fang‐Fang
Chen, Ling‐Yan
Sun, Peng
Lv, Yixin
Zhang, Yan‐Xue
Li, Jia‐Yu
Yin, Xiaoying
Li, Ya - Abstract:
- Abstract: A series of chiral 5‐hydroxy isoxazolidines has been successfully synthesized through camphor sulfonyl hydrazine‐catalyzed asymmetric aza‐Michael addition reaction between N, O ‐protected hydroxyamines and enals. Moderate yields with moderate to good enantioselectivities (up to 96% enantiomeric excess [ee]) were achieved. It provides an alternative asymmetric approach to preparing isoxazolidine derivatives. Abstract :
- Is Part Of:
- Chirality. Volume 32:Issue 3(2020)
- Journal:
- Chirality
- Issue:
- Volume 32:Issue 3(2020)
- Issue Display:
- Volume 32, Issue 3 (2020)
- Year:
- 2020
- Volume:
- 32
- Issue:
- 3
- Issue Sort Value:
- 2020-0032-0003-0000
- Page Start:
- 378
- Page End:
- 386
- Publication Date:
- 2020-01-20
- Subjects:
- 5‐hydroxyisoxazolidine -- aza‐Michael addition -- camphor sulfonyl hydrazine -- organocatalytic
Chirality -- Periodicals
Pharmaceutical chemistry -- Periodicals
541.22 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1520-636X ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/chir.23168 ↗
- Languages:
- English
- ISSNs:
- 0899-0042
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3181.124450
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 12797.xml