Atypical severe progressive perioral ulceration due to herpes simplex virus on the background of undiagnosed HIV/AIDS. (2nd July 2019)

• Record Type: Journal Article
• Authors: Howard, Matthew David; Poon, Flora; Milne, Olivia Jean; Kelmann, Anthony; Chong, Alvin H
• Is Part Of: Australasian journal of dermatology. Volume 61:Number 1(2020)
• Page Start: e79
• Page End: e81
• Publication Date: 2019-07-02
• Subjects: herpes simplex virus -- HIV -- HSV -- human immunodeficiency virus -- ulceration; Dermatology -- Periodicals; Dermatology -- Australasia -- Periodicals; 616.5005
• DOI: 10.1111/ajd.13111
• Languages: English
• ISSNs: 0004-8380

Abstract

Abstract: Perioral ulcerative plaques have a broad list of differential diagnoses. We describe an unusual presentation of chronic progressive perioral ulceration due to herpes simplex type (HSV)‐1 on a background of undiagnosed human immunodeficiency virus infection with acquired immunodeficiency syndrome. Whilst chronic mucocutaneous HSV is an AIDS‐defining condition with both HSV‐1 and HSV‐2 implicated, typical reported cases describe vesicular eruptions rather than perioral ulcerative plaques. This case highlights that common infections may present atypically in immunocompromised individuals and may be a clue to underlying systemic illness.