Additive-free coupling of bromoalkynes with secondary phosphine oxides to generate alkynylphosphine oxides in acetic anhydride. Issue 6 (27th January 2020)

• Record Type: Journal Article
• Authors: Ruan, Hongjie; Meng, Ling-Guo; Xu, Hailong; Liang, Yuqing; Wang, Lei
• Is Part Of: Organic & biomolecular chemistry. Volume 18:Issue 6(2020)
• Page Start: 1087
• Page End: 1090
• Publication Date: 2020-01-27
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c9ob02750e
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A coupling of bromoalkynes with secondary phosphine oxides was developed to generate alkynylphosphine oxides under additive-free conditions in acetic anhydride. Abstract : A coupling of bromoalkynes with secondary phosphine oxides was developed for the synthesis of alkynylphosphine oxides. This transformation was accomplished under additive-free conditions in acetic anhydride (Ac2 O). The reaction could be carried out under mild conditions, and a wide range of secondary phosphine oxides were obtained in good yields.