Alternatives to Transfusion: A Case Report and Brief History of Artificial Oxygen Carriers. Issue 3 (3rd November 2019)

• Record Type: Journal Article
• Authors: Bachert, Sara Emily; Dogra, Prerna; Boral, Leonard I
• Is Part Of: American journal of clinical pathology. Volume 153:Issue 3(2020)
• Page Start: 287
• Page End: 293
• Publication Date: 2019-11-03
• Subjects: Transfusion medicine -- Hemoglobin-based oxygen carriers -- Sanguinate; Diagnosis, Laboratory -- Periodicals; Pathology -- Periodicals; 616.07
• DOI: 10.1093/ajcp/aqz175
• Languages: English
• ISSNs: 0002-9173

Abstract

Abstract: Objectives: We discuss two main categories of blood substitutes: perfluorocarbons and hemoglobin-based oxygen carriers. Methods: We provide a review of the notable products developed in both categories and include their attributes as well as their setbacks. Results: We contribute a case report tothe growing literature of the successful use of Sanguinate. Conclusions: We find that artificial oxygen carriers are an attractive field of research because of the practical limitations and the multitude of potential complications that surround human blood transfusions.