Pathological Findings of Synchysis Scintillans Secondary to Familial Exudative Vitreoretinopathy With Chronic Exudative Retinal Detachment. (March 2020)

• Record Type: Journal Article
• Authors: Lin, James; Garcia, Armando; Chen, Ying; Dubovy, Sander; Lee, Wendy; Kopplin, Laura J.; Berrocal, Audina
• Is Part Of: Journal of vitreoretinal diseases. Volume 4:Number 2(2020)
• Page Start: 163
• Page End: 166
• Publication Date: 2020-03
• Subjects: cholesterolosis bulbi -- enucleation -- retinal detachment -- synchysis scintillans; Retina -- Diseases -- Periodicals; Vitreous body -- Diseases -- Periodicals; Retina -- Diseases; Vitreous body -- Diseases; Periodicals; 617.735005
• DOI: 10.1177/2474126419880385
• Languages: English
• ISSNs: 2474-1264

Abstract

Purpose: We describe a unique case of synchysis scintillans in a 23-year-old woman with a history of chronic exudative retinal detachment in the setting of familial exudative vitreoretinopathy. Methods: Fundus and slit-lamp photographs were obtained at presentation, and pathological studies were performed on the enucleated specimen to confirm the diagnosis. Results: Synchysis scintillans is a degenerative condition of cholesterol deposition that affects severely damaged eyes, often as a result of chronic vitreous hemorrhage or retinal detachment. In this case, synchysis scintillans presented as crystals in the anterior chamber in the setting of a chronic retinal detachment. After enucleation, there were noted to be cholesterol slits on pathological correlation, confirming the diagnosis. Conclusions: This case demonstrates the importance of clinical pathological correlation in the diagnosis of synchysis scintillans migrating into the anterior chamber.