Blepharospasm as the presenting feature of papillary thyroid cancer and parathyroid adenoma. (February 2020)

• Record Type: Journal Article
• Authors: Jamora, Roland Dominic G.; Espiritu, Adrian I.; Santiago, Janet J.; Wohldorf, Jocelyn J.; Cuanang, Joven R.
• Is Part Of: Journal of clinical neuroscience. Volume 72(2020)
• Page Start: 460
• Page End: 463
• Publication Date: 2020-02
• Subjects: Blepharospasm -- Papillary thyroid carcinoma -- Parathyroid adenoma -- Focal dystonia -- Case report; Brain -- Surgery -- Periodicals; Neurosciences -- Periodicals; Nervous system -- Surgery -- Periodicals; Brain -- surgery -- Periodicals; Neurosurgical Procedures -- Periodicals; Neurosciences -- Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.jocn.2019.12.025
• Languages: English
• ISSNs: 0967-5868

Abstract

Highlights: Blepharospasm is a focal dystonia presenting with orbicularis oculi hyperactivity with varied etiologies. We report a novel case of thyroid and parathyroid neoplasms that initially presented with blepharospasm. A work-up for these neoplasms may be warranted for patients with blepharospasm. Surgical removal of these masses offered a clinically significant control of the blepharospasm in our case. Abstract: Blepharospasm is a type of focal dystonia depicted by periodic and spontaneous closure of the orbicularis oculi and surrounding muscles. Typical secondary etiologies of blepharospasm may include ophthalmologic and structural brain lesions. In this article, we report a novel case of a patient with a biopsy-proven concurrent papillary carcinoma of the thyroid gland and adenoma of the parathyroid gland with blepharospasm as an exceptionally unique initial manifestation. This report showed that a diagnostic work-up for causes of blepharospasm may include a search for these neoplasm and surgical removal of these masses may offer significant symptomatic control of the focal dystonia.