Recent applications of chiral phosphoric acids in palladium catalysis. Issue 4 (7th January 2020)

• Record Type: Journal Article
• Authors: Tran, Van T.; Nimmagadda, Sri Krishna; Liu, Mingyu; Engle, Keary M.
• Is Part Of: Organic & biomolecular chemistry. Volume 18:Issue 4(2019)
• Page Start: 618
• Page End: 637
• Publication Date: 2020-01-07
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c9ob02205h
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A variety of catalytic asymmetric reactions have been realized during the past decade through the combined action of palladium and chiral phosphoric acids (CPAs). This review surveys key examples and examines the underlying mechanisms of stereoinduction. Abstract : Through the combined action of palladium catalysts and chiral phosphoric acids (CPAs) a variety of catalytic asymmetric reactions have been realized during the past decade, including allylation, alkene functionalization, and C–H activation. This review surveys key examples across these various reaction types and examines the different mechanisms by which CPAs can affect stereoinduction in these reaction systems.