A new hypervalent iodine(iii/v) oxidant and its application to the synthesis of 2H-azirines. Issue 4 (17th December 2019) - Zhang, Guangtao
Abstract : The reaction of o -nitroiodobenzene and m CPBA in AcOH was found to afford a novel hypervalent iodine compound which both iodine(iii ) and iodine(v ) moieties coexist. This new reagent is proved to be effective in realizing the synthesis of 2 H -azirines. Abstract : The reaction of o -nitroiodobenzene and m CPBA in acetic acid was found to afford a novel hypervalent iodine compound, in the structure of which both iodine(iii ) and iodine(v ) moieties coexist. The nitro groups at the ortho phenyl positions were found to be crucial in stabilizing this uncommon structure. This novel hypervalent iodine(iii /v ) oxidant is proved to be effective in realizing the synthesis of 2-unsubstitued 2 H -azirines via intramolecular oxidative azirination, which could not be efficiently achieved by the existing known hypervalent iodine reagents.