The complex challenges of HIV vaccine development require renewed and expanded global commitment. Issue 10221 (1st February 2020) - Bekker, Linda-Gail; Tatoud, Roger; Dabis, Francois; Feinberg, Mark; Kaleebu, Pontiano; Marovich, Mary; Ndung'u, Thumbi; Russell, Nina; Johnson, Jeremiah; Luba, Maureen; Fauci, Anthony S; Morris, Lynn; et al.