High-intensity aerobic training lowers blood pressure and modulates the renal renin-angiotensin system in spontaneously hypertensive rats. (2nd April 2020)

• Record Type: Journal Article
• Authors: Almeida, Jeeser Alves; Motta-Santos, Daisy; Petriz, Bernardo Assis; Gomes, Clarissa Pedrosa da Costa; Nogueira, Murilo Esteves; Pereira, Rinaldo Wellerson; Araújo, Ronaldo Carvalho; Prestes, Jonato; Franco, Octávio Luiz
• Is Part Of: Clinical and experimental hypertension. Volume 42:Number 3(2020)
• Page Start: 233
• Page End: 238
• Publication Date: 2020-04-02
• Subjects: Renin-angiotensin system -- high-intensity exercise -- blood pressure -- hypertension; Hypertension -- Chemotherapy -- Periodicals; Hypotensive agents -- Periodicals; 616.132
• DOI: 10.1080/10641963.2019.1619755
• Languages: English
• ISSNs: 1064-1963

Abstract

ABSTRACT: Background: This study aimed to verify the effects of high-intensity aerobic training (HIAT) on BP control and renin-angiotensin system (RAS) components in renal tissue of SHR. Ten SHRs received HIAT or control for 8-weeks. At the end of the training, the SBP showed a reduction of ~ 30mmHg (p < .01) in HIAT and increased by ~ 15 mmHg in the control group. HIAT resulted in a higher release of nitrite, IL-6, ACE2 and ATR2. These results indicated an association between BP, NO and renal RAS. Abbreviations : JAA: writing, carried out all experimental procedures, performed statistical analysis, original draft and revised manuscript DMS: data interpretation, formal analysis, writing, editing and revised manuscript BAP: carried all experimental procedures, revised manuscritpt CPCG: carried all experimental procedures, revised manuscritpt MEN: experimental procedures, revised manuscript and data interpretation RWP: drafted and revised manuscript RCA: writing, experimental procedures, revised manuscript JP: writing, data interpretation and revised manuscript OLF: writing, original draft and revised manuscript.