Demographic and Clinical Features of Pediatric Uveitis in Israel. (2nd January 2020)

• Record Type: Journal Article
• Authors: Habot-Wilner, Zohar; Tiosano, Liran; Sanchez, Juan M.; Shulman, Shiri; Barequet, Dana; Rahat, Ori; Amarilyo, Gil; Amer, Radgonde
• Is Part Of: Ocular immunology and inflammation. Volume 28:Number 1(2020)
• Page Start: 43
• Page End: 53
• Publication Date: 2020-01-02
• Subjects: Adolescents -- anterior uveitis -- children -- corticosteroids -- intermediate uveitis -- panuveitis -- posterior uveitis -- TNF-α inhibitors -- uveitis -- uveitis complications; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2018.1535079
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose : To report the epidemiology, etiology, ocular characteristics, treatment and visual outcome of pediatric uveitis in Israel. Methods : Retrospective study from two tertiary uveitis centers. Results : Included were 107 patients (182 eyes), 55% females. Mean age at diagnosis 8.8 years. Uveitis was predominantly anterior, idiopathic, bilateral, and chronic. Systemic associations were seen in 36% of patients of which the most common disease was juvenile idiopathic arthritis. Infectious uveitis accounted for 37% of posterior uveitis cases of which toxoplasmosis was the most common cause. Anterior segment complications were commonly observed at presentation (41%); the most predominant were posterior synechiae, cataract, and band keratopathy. The most common posterior segment complications were papillitis, epiretinal membrane, and macular atrophy/scar. Ninety-three percent of eyes had visual acuity >20/40 at last follow-up. Conclusion : The pattern of pediatric uveitis in Israel is similar to that in the western world. Visual outcome was good in most eyes.