Plant immune signaling: Advancing on two frontiers. Issue 1 (21st January 2020)

• Record Type: Journal Article
• Authors: Wang, Wei; Feng, Baomin; Zhou, Jian‐Min; Tang, Dingzhong
• Editors: Gong, Zhizhong
• Is Part Of: Journal of integrative plant biology. Volume 62:Issue 1(2020)
• Page Start: 2
• Page End: 24
• Publication Date: 2020-01-21
• Subjects: Plants -- Periodicals; Plants -- China -- Periodicals; Electronic journals; 580.5
• DOI: 10.1111/jipb.12898
• Languages: English
• ISSNs: 1672-9072

Abstract

Abstract : In nature, plants are constantly exposed to pathogens thus have evolved multiple defense strategies to cope with pathogens, including plant immune signaling that relies on cell‐surface localized pattern recognition receptors (PRRs) and intracellular NLR immune receptors. This review mainly summarized the current views of PRRsactivated immunity and the mechanisms of NLRs activation. Abstract: Plants have evolved multiple defense strategies to cope with pathogens, among which plant immune signaling that relies on cell‐surface localized and intracellular receptors takes fundamental roles. Exciting breakthroughs were made recently on the signaling mechanisms of pattern recognition receptors (PRRs) and intracellular nucleotide‐binding site (NBS) and leucine‐rich repeat (LRR) domain receptors (NLRs). This review summarizes the current view of PRRs activation, emphasizing the most recent discoveries about PRRs' dynamic regulation and signaling mechanisms directly leading to downstream molecular events including mitogen‐activated protein kinase (MAPK) activation and calcium (Ca 2+ ) burst. Plants also have evolved intracellular NLRs to perceive the presence of specific pathogen effectors and trigger more robust immune responses. We also discuss the current understanding of the mechanisms of NLR activation, which has been greatly advanced by recent breakthroughs including structures of the first full‐length plant NLR complex, findings of NLR sensor‐helper pairs and novel biochemical activity of Toll/interleukin‐1 receptor (TIR) domain.