One-pot synthesis of a new generation of hybrid bisphosphonate polyoxometalate gold nanoparticles as antibiofilm agents. Issue 9 (28th August 2019)

• Record Type: Journal Article
• Authors: Tomane, S.; López-Maya, E.; Boujday, S.; Humblot, V.; Marrot, J.; Rabasso, N.; Castells-Gil, J.; Sicard, C.; Dolbecq, A.; Mialane, P.; Vallée, A.
• Is Part Of: Nanoscale advances. Volume 1:Issue 9(2019)
• Page Start: 3400
• Page End: 3405
• Publication Date: 2019-08-28
• Subjects: 620.5
• DOI: 10.1039/c9na00401g
• Languages: English
• ISSNs: 2516-0230

Abstract

Abstract : A reduced polyoxovanadate functionalized with alendronate molecules was used for the synthesis of gold nanoparticles; these hybrid nanomaterials exhibit high antibiofilm activity. Abstract : A reduced polyoxovanadate functionalized with bisphosphonate molecules was synthesized and used to prepare in one step hybrid organic–inorganic polyoxometalate decorated gold nanoparticles. These new composites were shown to strongly inhibit P. aeruginosa and S. epidermidis biofilm growth, with the three components constituting the nanoparticles (Au 0 core, vanadium and alendronate) acting synergistically.