Mycobacterium chimaera Encephalitis Following Cardiac Surgery: A New Syndrome. (18th June 2019)

• Record Type: Journal Article
• Authors: Lau, Darren; Cooper, Ryan; Chen, Justin; Sim, Valerie L; McCombe, Jennifer A; Tyrrell, Gregory J; Bhargava, Ravi; Adam, Benjamin; Chapman, Erin; Croxen, Matthew A; Garady, Cherif; Antonation, Kym; van Landeghem, Frank K H; Ip, Shannon; Saxinger, Lynora
• Is Part Of: Clinical infectious diseases. Volume 70:Number 4(2020)
• Page Start: 692
• Page End: 695
• Publication Date: 2019-06-18
• Subjects: Mycobacterium chimaera -- infection prevention and control -- granulomatous encephalitis -- post operative infections -- cardiopulmonary bypass; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciz497
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: We report the cases of 3 patients with fatal, disseminated Mycobacterium chimaera infections following cardiac surgeries. Progressive neurocognitive decline and death were explained by active granulomatous encephalitis, with widespread involvement of other organs. This syndrome is clinically elusive and, thus, may have caused deaths in prior reported series.