Catalytic Production of Alanine from Waste Glycerol. (27th December 2019)

• Record Type: Journal Article
• Authors: Wang, Yunzhu; Furukawa, Shinya; Song, Song; He, Qian; Asakura, Hiroyuki; Yan, Ning
• Is Part Of: Angewandte Chemie. Volume 132:Number 6(2020)
• Page Start: 2309
• Page End: 2313
• Publication Date: 2019-12-27
• Subjects: Aminosäuren -- Biomasse -- Glycerol -- Heterogene Katalyse -- Oberflächenchemie; Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201912580
• Languages: English
• ISSNs: 0044-8249

Abstract

Abstract: Chemical synthesis of amino acids directly from biomass feedstock is rare. Reported here is a one‐step protocol to convert crude glycerol, from the biodiesel industry, into 43 % alanine over a Ru1 Ni7 /MgO catalyst. The multifunctional catalytic system promotes glycerol conversion into lactic acid, and then into alanine. X‐ray absorption spectroscopy and scanning transmission electron microscopy revealed the existence of bimetallic RuNi species, whereas density‐functional theory calculations suggested Ni‐doped Ru substantially decreased the E a of C−H bond dissociation of lactate alkoxide to form pyruvate, which is the rate‐determining step. The catalytic route established in this work creates new opportunities for glycerol utilization and enriches the substrate scope of renewable feedstock to access value‐added amino acids. Abstract : Direkte Umwandlung : 43 % Alanin wurden aus Rohglycerin über einem Ru1 Ni7 /MgO‐Katalysator gewonnen. Bemerkenswerterweise katalyiserte Ni‐dotiertes Ru die Milchsäure‐Aminierung, einen wichtigen Schritt in der Reaktion. Der Katalyseweg eröffnet neue Möglichkeiten für die Glycerinverwertung und bereichert den Substratbereich nachwachsender Rohstoffe mit dem Zugang zu wertvollen Aminosäuren.