Selective Colour Vision Deficits in Multiple Sclerosis at Different Temporal Stages. (2nd January 2020)

• Record Type: Journal Article
• Authors: Anssari, Neda; Vosoughi, Reza; Mullen, Kathy; Mansouri, Behzad
• Is Part Of: Neuro-ophthalmology. Volume 44:Number 1(2020)
• Page Start: 16
• Page End: 23
• Publication Date: 2020-01-02
• Subjects: Multiple sclerosis -- red/green -- blue/yellow -- colour vision -- psychophysics; Neuroophthalmology -- Periodicals; 617.7
• DOI: 10.1080/01658107.2019.1615960
• Languages: English
• ISSNs: 0165-8107

Abstract

ABSTRACT: Multiple sclerosis (MS) without optic neuritis causes color-vision deficit but the evidence for selective color deficits in parvocellular-Red/Green (PC-RG) and koniocellular-Blue/Yellow (KC-BY) pathways is inconclusive. We investigated selective color-vision deficits at different MS stages. Thirty-one MS and twenty normal participants were tested for achromatic, red-green and blue-yellow sinewave-gratings (0.5 and 2 cycles-per-degree (cpd)) contrast orientation discrimination threshold. Red-green mean threshold at 0.5cpd in established-MS and blue-yellow mean threshold in all MS participants were abnormal. These findings show blue-yellow versus red-green color test is useful in differentiating MS chronicity, which helps to better understand the mechanism of colour-vision involvement in MS.