Coronary artery decision algorithm trained by two-step machine learning algorithm. Issue 7 (24th January 2020)

• Record Type: Journal Article
• Authors: Kim, Young Woo; Yu, Hee-Jin; Kim, Jung-Sun; Ha, Jinyong; Choi, Jongeun; Lee, Joon Sang
• Is Part Of: RSC advances. Volume 10:Issue 7(2020)
• Page Start: 4014
• Page End: 4022
• Publication Date: 2020-01-24
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c9ra08999c
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A two-step machine learning (ML) algorithm for coronary artery decision making is introduced, to increase the data quality by providing flow characteristics and biometric features by aid of computational fluid dynamics (CFD). Abstract : A two-step machine learning (ML) algorithm for estimating both fractional flow reserve (FFR) and decision (DEC) for the coronary artery is introduced in this study. The primary purpose of this model is to suggest the possibility of ML-based FFR to be more accurate than the FFR calculation technique based on a computational fluid dynamics (CFD) method. For this purpose, a two-step ML algorithm that considers the flow characteristics and biometric features as input features of the ML model is designed. The first step of the algorithm is based on the Gaussian progress regression model and is trained by a synthetic model using CFD analysis. The second step of the algorithm is based on a support vector machine with patient data, including flow characteristics and biometric features. Consequently, the accuracy of the FFR estimated from the first step of the algorithm was similar to that of the CFD-based method, while the accuracy of DEC in the second step was improved. This improvement in accuracy was analyzed using flow characteristics and biometric features.