Controlling the kinetics of interaction between microtubules and kinesins over a wide temperature range using the deep-sea osmolyte trimethylamine N-oxide. Issue 8 (10th January 2020)

• Record Type: Journal Article
• Authors: Munmun, Tasrina; Kabir, Arif Md. Rashedul; Katsumoto, Yukiteru; Sada, Kazuki; Kakugo, Akira
• Is Part Of: Chemical communications. Volume 56:Issue 8(2020)
• Page Start: 1187
• Page End: 1190
• Publication Date: 2020-01-10
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc09324a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Trimethylamine N -oxide (TMAO) is found to be effective in regulating the kinetics of interaction between microtubules and kinesins over a wide temperature range. Abstract : Trimethylamine N -oxide is found to be effective in regulating the interaction between microtubules and kinesins over a wide temperature range. The lifetime of the motility of microtubules on kinesins at high temperatures is prolonged using trimethylamine N -oxide. The activation energy of microtubule motility is increased by trimethylamine N -oxide. Prolonged operation at high temperatures decreased the activation energy of MT motility despite the increase in concentration of trimethylamine N -oxide.