Progress in understanding the relationship between long noncoding RNA and endometriosis. (January 2020)

• Record Type: Journal Article
• Authors: Yan, Wenying; Hu, Hongmei; Tang, Biao
• Is Part Of: European journal of obstetrics and gynecology and reproductive biology X. Volume 5(2020)
• Publication Date: 2020-01
• Subjects: EMs Endometriosis -- lncRNAs long non-coding RNAs -- ncRNAs non-coding RNAs -- snRNAs small nuclear RNAs -- piRNAs PIWI-interacting RNAs -- siRNAs short inhibitory RNAs -- NATs natural antisense transcripts -- Igf2 insulin-like growth factor 2 -- Igf1r insulin-like growth factor-1 receptor -- CDK6 cyclin dependent kinase 6 -- SRA Steroid receptor RNA activator -- SRAP steroid receptor activator protein -- HIF-1α Hypoxia inducible factor-1alpha; Endometriosis -- Non-coding RNA -- lncRNAs -- Early diagnosis
• DOI: 10.1016/j.eurox.2019.100067
• Languages: English
• ISSNs: 2590-1613

Abstract

Abstract: Endometriosis is a common gynecological disease. However, the etiology of endometriosis is still unclear, and current theories cannot fully elaborate its specific pathogenesis. Recently, some research has suggested that the occurrence and development of endometriosis may be related to genetics. Long-chain non-coding RNA (lncRNAs) is a kind of non-protein-coding RNA molecule with a length of 200-100, 000 bp. With complex biological functions, lncRNAs play an important role in the normal development of individuals and the progression of various diseases, and lncRNAs have become an important field of medical research in recent years. This paper mainly illustrates the research progress on lncRNAs as they relate to endometriosis. We also provide some ideas for exploring the pathogenesis of endometriosis.