CRISPR-TSKO: A Tool for Tissue-Specific Genome Editing in Plants. (February 2020)

• Record Type: Journal Article
• Authors: Ali, Zahir; Mahfouz, Magdy M.; Mansoor, Shahid
• Is Part Of: Trends in plant science. Volume 25:Number 2(2020)
• Page Start: 123
• Page End: 126
• Publication Date: 2020-02
• Subjects: functional genomics -- genome editing -- CRISPR-Cas9 -- CRISPR-TSKO; Botany -- Periodicals; Botanique -- Périodiques; Botany; Periodicals; 580.5
• DOI: 10.1016/j.tplants.2019.12.002
• Languages: English
• ISSNs: 1360-1385

Abstract

Abstract : Functional genomics is at the core of studying the exact function of genes. However, homozygous knockouts of essential and pleiotropic effectors (almost 10% of the genome) are not always possible, thus, functions of these genes remain obscured. The tissue-specific genome editing tool (CRISPR-TSKO) recently described by Decaestecker et al., can characterize these indispensable genes and has wide applications in plants.