Single cell sequencing shines a light on malaria parasite relatedness in complex infections. Issue 2 (February 2020)

• Record Type: Journal Article
• Authors: Siegel, Sasha V.; Rayner, Julian C.
• Is Part Of: Trends in parasitology. Volume 36:Issue 2(2020)
• Page Start: 83
• Page End: 85
• Publication Date: 2020-02
• Subjects: malaria -- relatedness -- complexity of infection (COI) -- co-transmission -- superinfection -- single cell sequencing; Parasitology -- Periodicals; Parasitology -- Periodicals; Biology -- Periodicals; Parasitology; Biology; Parasitologie -- Périodiques; Online resources; 571.999
• DOI: 10.1016/j.pt.2019.12.007
• Languages: English
• ISSNs: 1471-4922

Abstract

Abstract : Recent genomic studies are investigating the wide-ranging implications of malaria complex infections on parasite diversity, transmission, and downstream disease eradication efforts. Using single cell sequencing, new work by Nkhoma et al. provides evidence that there is unexpectedly frequent co-transmission of related parasites in the intense transmission setting in Malawi.