Post‐Pump Chorea and Progressive Supranuclear Palsy‐Like Syndrome Following Major Cardiac Surgery. Issue 1 (11th December 2019)

• Record Type: Journal Article
• Authors: Park, Kye Won; Choi, Nari; Ryu, Ho‐Sung; Kim, Ho Jin; Lee, Chong S.; Chung, Sun Ju
• Is Part Of: Movement disorders clinical practice. Volume 7:Issue 1(2020)
• Page Start: 78
• Page End: 82
• Publication Date: 2019-12-11
• Subjects: Post‐pump chorea -- progressive supranuclear palsy -- cardiopulmonary bypass -- deep hypothermia circulatory arrest; Movement Disorders; Movement disorders -- Periodicals; Movement disorders; Periodicals; Periodicals; 616
• DOI: 10.1002/mdc3.12867
• Languages: English
• ISSNs: 2330-1619

Abstract

ABSTRACT: Background: Post‐pump chorea and progressive‐supranuclear palsy (PSP)–like syndrome after aortic surgery are 2 distinct movement disorders following major cardiac surgeries. Cases: We herein report 3 patients with movement disorders that developed after major cardiac surgeries. Two patients developed post‐pump chorea after pulmonary endarterectomy, and 1 further case developed PSP‐like syndrome after aortic replacement surgery. The 2 conditions share several common aspects. Both are preceded by surgeries that undergo cardiopulmonary bypass and deep hypothermia circulatory arrest procedures. Most cases present with biphasic course. However, post‐pump chorea occurs in all age populations after any surgeries that undergo deep hypothermia circulatory arrest, whereas PSP‐like syndrome is reported exclusively in the adult population after aortic surgery. Conclusions: Post‐pump chorea and PSP‐like syndrome are neurologic complications of major cardiac surgeries that should not be underrecognized. Further reports to establish their common pathogenic mechanism should be encouraged. Abstract : View Supplementary Video 1 View Supplementary Video 2 View Supplementary Video 3